VENUS ZAFARİ

Motivated student currently working towards a degree in Metastasis of cancer cells. Detail-oriented Research Assistant with hands-on experience performing clerical and laboratory work to advance research goals. Drives team success with data review, reporting, and specimen-handling expertise. Adept at prepping resources, equipment, and materials for research. Extensive background in investigating alterations of gene expression level during carcinogenesis using various methods like qPCR, Western blot, etc., and also, seeking to find new novel biomarkers for early detection of cancer patients before manifestation of symptoms.

• Oliyaierezaie A, Zarredar H, Asadi M, Zafari V, Shanebandi D, Soleimani Z, Firoozi MR, Gasembeglo S. Evaluation of Potential miR-302, miR-132, miR-205, and miR-126 as Biomarkers for Laryngeal Squamous Cell Carcinoma. International Journal of Cancer Management. 2023 Dec 31;16(1).
• Asadi M, Zarredar H, Zafari V, Soleimani Z, Saeedi H, Caner A, Shanehbandi D. Immune Features of Tumor Microenvironment: A Genetic Spotlight. Cell Biochemistry and Biophysics. 2023 Oct 23:1-2.
• Ghoushouni S, Sharifi A, Zafari V, Zarredar H, Seyedrezazadeh E. Association of the Toll-like receptor 4 and NOX4 gene and protein levels in asthmatic patients with metabolic syndrome: A case–control study. Journal of Research in Medical Sciences: The Official Journal of Isfahan University of Medical Sciences. 2023;28.
• Shanehbandi D, Asadi M, Seyedrezazadeh E, Zafari V, Shekari N, Akbari M, Rahbarnia L, Zarredar H. microRNA-based biomarkers in lung cancer: recent advances and potential applications. Current Molecular Medicine. 2023 Aug 1;23(7):648-67.
• Motamediyan K, Zafari V, Bornehdeli S, Caner A, Asadi M, Hashemzadeh S, Firozi MR, Raeisi M. Evaluation of expression levels of NFATc2 and PPARG genes two effector elements of WNT pathway in non-small cell lung carcinoma. Advanced Biomedical Research. 2023 Jul 1;12(1):184.
• Zarredar H, Asadi M, Shanehbandi D, Zafari V, Bornodeli S, Soleimani Z, Ghasembaglou S. Evaluation of the LncRNA TMPO AS-1 Expression Level in Melanoma Tissues in Comparison to Paired Normal Marginal Tissues. Middle East Journal of Cancer. 2023 Jul 1;14(3):399-404.
• Zafari V, Asadi M, Bakhtiyari N, Sadeghzadeh M, Khalili M, Zarredar H, Bornehdeli S, Seyedrezazadeh E. Regulatory Effect of let-7f Transfection in Non-Small Cell Lung Cancer on its Candidate Target Genes. Iranian biomedical journal. 2022 May 1;26(3):209-18.
• Sabeti Z, Ansarin K, Seyedrezazadeh E, Jafarabadi MA, Zafari V, Dastgiri S, Shakerkhatibi M, Gholampour A, Khamnian Z, Sepehri M, Dahim M, Sharbafi J, Hakimi D. Acute responses of airway oxidative stress, inflammation, and hemodynamic markers to ambient PM2.5 and their trace metal contents among healthy adolescences: A panel study in highly polluted versus low polluted regions. Environ Pollut. 2021 Nov 1;288:117797. doi: 10.1016/j.envpol.2021.117797. Epub 2021 Jul 16. PMID: 34329054.
• Kamran S, Seyedrezazadeh E, Shanehbandi D, Asadi M, Zafari V, Shekari N, Namvar L, Zarredar H. Combination Therapy with KRAS and P38α siRNA Suppresses Colorectal Cancer Growth and Development in SW480 Cell Line. J Gastrointest Cancer. 2021 Jul 22. doi: 10.1007/s12029-021-00667- 1. Epub ahead of print. PMID: 34292499.
• Karimi L, Jaberi M, Asadi M, Zarredar H, Zafari V, Bornehdeli S, Niknam S, Kermani TA. Significance of microRNA-330/TYMS expression axis through colorectal tumorigenesis. Research Square; 2021. DOI: 10.21203/rs.3.rs-501698/v1.
• Zarredar H, Khamaneh A, Firouzi Amoodizaj F, Shanaehband D, Seyedrezazadeh E, Sabagh Jadid H, Asadi M, Zafari V, Khalili Y, Soleimani Z, Ansarin A, khalili M. Terminalia Catappa Extract (TCE) Reduces Proliferation of Lung and Breast Cancer Cell by Modulating miR-21 and miR-34a Expressions. Asian Pacific Journal of Cancer Prevention, 2021; 22(4): 1157-1163. doi: 10.31557/APJCP.2021.22.4.1157
• Safaei S, Shanehbandi D, Zafari V, Eghbali E, Sadeghzadeh M, Mohammad Reza Khani H, et al. Evaluation of miR-107, DAPK1 and KLF4 expression in colorectal tumors and effect of oxaliplatin and 5-FU on their levels in colorectal cancer cell lines. Middle East J Cancer. 2021; 12(2): 190-7. doi: 10.30476/mejc.2020.83091.1131. Laboratory and Research Proficiency: Publications:
• Bakhtiyari N, Zafari V, A Sharifi, Bornedeli S, Seyedrezazadeh E. Up-regulation of oxysterolbinding protein 3 in lung tissue of patients with non-small lung cancer, Gene Reports, Volume 22, 2021, 100998. https://doi.org/10.1016/j.genrep.2020.100998.
• Aftabi Y, Ansarin K, Shanehbandi D, Khalili M, Seyedrezazadeh E, Rahbarnia L, Asadi M, AmiriSadeghan A, Zafari V, Eyvazi S, Bakhtiyari N, Zarredar H. Long non-coding RNAs as potential biomarkers in the prognosis and diagnosis of lung cancer: A review and target analysis. IUBMB Life. 2021 Feb;73(2):307-327. doi: 10.1002/iub.2430. Epub 2020 Dec 24. PMID: 33369006.
• Sabeti Z, Ansarin K, Seyedrezazadeh E, Asghari Jafarabadi M, Zafari V, Dastgiri S, Shakerkhatibi M, Gholampour A, Ghanbari Ghozikali M, Ghasemzadeh R, Torabi Y, Mohammadi B. (2021) A comparison of asthma prevalence in adolescents living in urban and semi-urban areas in northwestern Iran, Human and Ecological Risk Assessment: An International Journal, DOI: 10.1080/10807039.2021.1944051.
• Zafari V, Shanehbandi D, Bornehdeli S, Sadeghzadeh M, Zarredar H, Asadi M, Sharifi A. MicroRNA Profiling in Non-Small Cell Lung Cancer and its Implications for the Disease Pathogenesis. Middle East Journal of Cancer. 2020 Aug 23.
• Zafari V, Zarredar H, Poursaei E, Abolghasemi M, Shanehbandi D, Bornehdeli S, Asadi M, Sharifi A. Evaluating of miR-184, miR-497, miR-378, miR-103 and miR-506 expression level in non-small cell lung cancer patients tissues compared with their normal marginal tissues. Gene Reports. 2020 Jun 12:100750.
• Zafari V, Hashemzadeh S, Pouladi N, Sakhinia E. mRNA expression of nuclear factor of activated T-cells, cytoplasmic 2 (NFATc2) and peroxisome proliferator-activated receptor gamma (PPARG) transcription factors in colorectal carcinoma. Bosnian Journal of Basic Medical Sciences. 2017 Aug 20;17(3):255-61.
• Azar MR, Akbari M, Mohammed HN, Asadi M, Shanehbandi D, Rezai M, Zafari V, Niknam S, Tamjidifar R, Tarzi S, Mahdavi F. Dysregulation of miR-27a and SMAD2 can be a reliable indicator in the prognosis and diagnosis of CRC as well as in response to chemotherapy drugs. Gene Reports. 2020 Dec 1;21:100844.
• Vafadar S, Zafari V, Pour Moghaddam M, Assadi M, Mahboob SA, Sharifi A, Seyedrezazadeh E. Expression Changes of miR-146a-5p and miR-196a-2 in Non-small Cell Lung Cancer Patients: A Casecontrol Study. Middle East Journal of Cancer. 2020 Aug 5.
• Pashapour S, Shanehbandi D, Bornehdeli S, Zafari V, Mohammad Reza Khan H, Hashemzadeh S, Asvadi Kermani T. Overexpression of HOTAIR in Tumor Tissues of Patients with Colon Cancer Correlates with Tumor Metastasis and Differentiation. Middle East Journal of Cancer. 2020 Jul 20.
• Sadeghzadeh M, Bornehdeli S, Mohahammadrezakhani H, Abolghasemi M, Poursaei E, Asadi M, Zafari V, Aghebati-Maleki L, Shanehbandi D. Dendritic cell therapy in cancer treatment; the state-ofthe-art. Life Sciences. 2020 Mar 20:117580.
• Alizadeh N, Asadi M, Shanehbandi D, Zafari V, Shomali N, Asvadi T, Sepehri B. Evaluation of the Methylation of MIR129-2 Gene in Gastric Cancer. Journal of Gastrointestinal Cancer. 2020 Mar;51(1):267-70.
• Shanehbandi D, Zarredar H, Asadi M, Zafari V, Esmaeili S, Seyedrezazadeh E, Soleimani Z, Jadid HS, Eyvazi S, Feyziniya S, Moghadam SB. Anticancer Impacts of Terminalia catappa Extract on SW480 Colorectal Neoplasm Cell Line. Journal of Gastrointestinal Cancer. 2019 Dec 10:1-7.
• Asadi M, Shanehbandi D, Zafari V, Khaze V, Somi MH, Hashemzadeh S. Transcript level of MicroRNA processing elements in gastric cancer. Journal of gastrointestinal cancer. 2019 Dec;50(4):855-9.
• Asadi M, Shanehbandi D, Zafari V, Khaze V, Somi MH, Hashemzadeh S. Transcript level of MicroRNA processing elements in gastric cancer. Journal of gastrointestinal cancer. 2019 Dec;50(4):855-9.
• Asadi M, Shanehbandi D, Kermani TA, Sanaat Z, Zafari V, Hashemzadeh S. Expression level of caspase genes in colorectal cancer. Asian Pacific journal of cancer prevention: APJCP. 2018;19(5):1277.
• Asadi M, Shanehbandi D, Zarintan A, Pedram N, Baradaran B, Zafari V, Shirmohamadi M, Hashemzadeh S. TP53Gene Pro72Arg (rs1042522) Single Nucleotide Polymorphism as Not a Risk Factor for Colorectal Cancer in the Iranian Azari Population. Asian Pacific journal of cancer prevention: APJCP. 2017;18(12):3423.
• Asadi M, Talesh S.T, Gjerstorff M.F, Shanehbandi D, Baradaran B, Hashemzadeh S, Zafari V. Identification of miRNAs correlating with stage and progression of colorectal cancer. Colorectal Cancer. 2019;8(2),[ CRC06]. https://doi.org/10.2217/crc-2018-0014.

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• Persian