Mehmet SAHIN

Molecular biologist with a strong background of immunology and viral infections. 8 years of experience in a virology lab which conducts leading basic research projects on virus-host interactions, viral vector-based vaccines and antibody protection. Expert in in vivo models, viral vector technologies, antibody discovery, antibody engineering, binding assays and protein purification methods. Outgoing, proactive, trustworthy, passionate team player with excellent listening, analytical thinking, problem-solving skills.

Microsoft Office and Applications

Endnote, LaTex

Adobe Illustrator, Adobe PS

GraphPad Prism

FlowJo, FACS Diva

DNASTAR Lasergene, UNICORN

MATLAB, JAVA, R, Python

Immunology, virology, antibody therapeutics, drug discovery, cancer immunotherapy, autoimmune diseases

• Graduated in the first place from High School
• Science Undergraduate Fellowship, awarded by TUBITAK
• Ranked 585th in (OYS) Nation-Wide Placement Examination among ~1.600.000 attendees
• Full Scholarship (BSc and MSc), awarded by Bilkent University and TUBITAK

• November 2011- 17th International Symposium on Biomedical Science and Technology, Ankara, Turkey (Poster presentation- Best Poster Award)
• May 2016- Department of Biomedicine PhD Retreat, Emmetten, Switzerland (Poster Presentation)
• October 2016- SIICA Viral Immunity Symposium, Milan, Italy (Poster Presentation)
• November 2016- UniBasel Immunology Community Retreat, Engelberg, Switzerland (Poster Presentation)
• May 2017- Department of Biomedicine PhD Retreat, Quarten, Switzerland (Oral Presentation)
• October 2017- Cell Symposia on Emerging & Re-emerging Viruses, Arlington, VA, USA (Oral Presentation–Biotechne Travel Award)
• March 2019- 29th Annual Meeting of the Society of Virology, Dusseldorf, Germany (Oral Presentation)

• Microbiology Lab Tutoring at Bilkent University (2012-2013)
• Immunology Lab Tutoring at University of Basel (2016-2021)
• Reviewer for Nature Communications Biology

• Sahin, M., Remy M.M., Fallet B., ..., Pinschewer D.D. (2022). Antibody bivalency improves antiviral efficacy by inhibiting viral release independently of Fc gamma receptors. Cell Reports 38.5 (2022): 1103033

• Weng M. Ng*, Mehmet Sahin*, Stefanie A. Krumm, ..., Daniel D. Pinschewer, Katie J. Doores, Thomas A. Bowden (2021). Contrasting modes of New World arenavirus neutralization by infection-elicited monoclonal antibodies. mBio 13.2 (2022): e02650-21 (*:shared first authorship)

• Sahin, M., Remy, M. M., Merkler, D., & Pinschewer, D. D. (2021). The Janus Kinase Inhibitor Ruxolitinib Prevents Terminal Shock in a Mouse Model of Arenavirus Hemorrhagic Fever. Microorganisms, 9(3), 564.

• Sommerstein, R., Flatz, L., Remy, M.M., Malinge, P., Magistrelli, G., Fischer, N., Sahin, M., …, Pinschewer, D. D., 2015. Arenavirus glycan shield promotes neutralizing antibody evasion and protracted infection. PLoS pathogens, 11(11), p.e1005276.

• Zeltina, A., Krumm, S.A., Sahin, M., Struwe, W.B., Harlos, K., Nunberg, J.H., Pinschewer, D.D., Doores, K.J. and Bowden, T.A., 2017. Convergent immunological solutions to Argentine hemorrhagic fever virus neutralization. Proceedings of the National Academy of Sciences, p.201702127.

• Melissa M. Remy*, Mehmet Sahin*, Lukas Flatz*, Tommy Regen, …, Doron Merkler, Daniel D. Pinschewer. 2017,

Interferon-g-driven iNOS: a molecular pathway to terminal shock in arenavirus hemorrhagic fever. Cell host & microbe. 22(3), pp.354-365. (*:shared first authorship)

• Khamina, K., Lercher, A., Caldera, M., Schliehe, C., Vilagos, B., Sahin, M., Kosack, L., Stukalov, A. and Sacco, R., 2017. Characterization of host proteins interacting with the lymphocytic choriomeningitis virus L protein. PLoS Pathogens, 13(12), p.e1006758.

Badminton, hiking, rock climbing, soccer, fitness, reading, baking