Summary
Overview
Work History
Education
Skills
Awards
Publications
Application
Software
Timeline
Generic
Derya Osmaniye

Derya Osmaniye

Academician
Eskişehir

Summary

- Osmaniye, D., Yuva, O., Sağlık, B. N., Levent, S., Ozkay, Y., & Kaplancıklı, Z. A. (2024). Design, synthesis, evaluation of biological activities and molecular docking and dynamic studies of novel acetazolamide analog compounds. Journal of Biomolecular Structure and Dynamics, 42(14), 7243-7256.

- Osmaniye, D., Ali, S. J. H., Çelikateş, B. K., Ilgın, S., Özkay, Y., & Kaplancıklı, Z. A. (2024). Investigation of Anticancer Effects of Novel Piperidine-Oxadiazole and Piperidine-Triazole Derivatives as VEGFR Inhibitors and Evaluation of Their Molecular Docking-Dynamic Studies. Journal of Molecular Structure, 139012.

- Osmaniye, D., Baltacı Bozkurt, N., Levent, S., Benli Yardımcı, G., Sağlık, B. N., Ozkay, Y., & Kaplancıklı, Z. A. (2023). Synthesis, antifungal activities, molecular docking and molecular dynamic studies of novel quinoxaline-triazole compounds. ACS omega, 8(27), 24573-24585.

- Osmaniye, D., Sağlık, B. N., Khalilova, N., Levent, S., Bayazıt, G., Gul, U. D., ... & Kaplancıklı, Z. A. (2023). Design, synthesis, and biological evaluation studies of novel naphthalene-chalcone hybrids as antimicrobial, anticandidal, anticancer, and VEGFR-2 inhibitors. ACS omega, 8(7), 6669-6678.

- Osmaniye, D., Evren, A. E., Karaca, Ş., Özkay, Y., & Kaplancıklı, Z. A. (2023). Novel thiadiazol derivatives; design, synthesis, biological activity, molecular docking and molecular dynamics. Journal of Molecular Structure, 1272, 134171.

- Osmaniye, D., Levent, S., Sağlık, B. N., Görgülü, Ş., Özkay, Y., & Kaplancıklı, Z. A. (2023). Synthesis of novel thiazol-2 (3 H)-imine derivatives as ergosterol biosynthesis inhibitors, and elucidation of their structures using a 2D NMR technique. New Journal of Chemistry, 47(37), 17558-17566.

- Osmaniye, D., Türkeş, C., Demir, Y., Özkay, Y., Beydemir, Ş., & Kaplancıklı, Z. A. (2022). Design, synthesis, and biological activity of novel dithiocarbamate‐methylsulfonyl hybrids as carbonic anhydrase inhibitors. Archiv der Pharmazie, 355(8), 2200132.

- Osmaniye, D., Karaca, Ş., Kurban, B., Baysal, M., Ahmad, I., Patel, H., ... & Kaplancıklı, Z. A. (2022). Design, synthesis, molecular docking and molecular dynamics studies of novel triazolothiadiazine derivatives containing furan or thiophene rings as anticancer agents. Bioorganic Chemistry, 122, 105709.

- Osmaniye, D., Evren, A. E., Sağlık, B. N., Levent, S., Özkay, Y., & Kaplancıklı, Z. A. (2022). Design, synthesis, biological activity, molecular docking, and molecular dynamics of novel benzimidazole derivatives as potential AChE/MAO‐B dual inhibitors. Archiv der Pharmazie, 355(3), 2100450.

- Osmaniye, D., Levent, S., Sağlık, B. N., Karaduman, A. B., Özkay, Y., & Kaplancıklı, Z. A. (2022). Novel imidazole derivatives as potential aromatase and monoamine oxidase-B inhibitors against breast cancer. New Journal of Chemistry, 46(16), 7442-7451.

- Osmaniye, D., Görgülü, Ş., Sağlık, B. N., Levent, S., Özkay, Y., & Kaplancıklı, Z. A. (2021). Design, synthesis, in vitro and in silico studies of some novel thiazole-dihydrofuran derivatives as aromatase inhibitors. Bioorganic Chemistry, 114, 105123.

- Osmaniye, D., Çelikateş, B. K., Sağlık, B. N., Levent, S., Çevik, U. A., Çavuşoğlu, B. K., ... & Kaplancıklı, Z. A. (2021). Synthesis of some new benzoxazole derivatives and investigation of their anticancer activities. European Journal of Medicinal Chemistry, 210, 112979.

- Can, N. Ö., Osmaniye, D., Levent, S., Sağlık, B. N., Korkut, B., Atlı, Ö., ... & Kaplancıklı, Z. A. (2018). Design, synthesis and biological assessment of new thiazolylhydrazine derivatives as selective and reversible hMAO-A inhibitors. European journal of medicinal chemistry, 144, 68-81.

- Can, Ö. D., Osmaniye, D., Özkay, Ü. D., Sağlık, B. N., Levent, S., Ilgın, S., ... & Kaplancıklı, Z. A. (2017). MAO enzymes inhibitory activity of new benzimidazole derivatives including hydrazone and propargyl side chains. European journal of medicinal chemistry, 131, 92-106.

Overview

8
8
years of professional experience

Work History

Associate Professor of Pharmacy

Anadolu University
03.2017 - Current

-Anadolu University, Faculty of Pharmacy, Department of Pharmaceutical Chemistry, Associate Professor
-Anadolu University, Faculty of Pharmacy, Vice Dean

Education

Ph.D. - Medicinal And Pharmaceutical Chemistry

Anadolu University Health Sciences Institute
04-2021

Master of Science - Medicinal And Pharmaceutical Chemistry

Anadolu University Health Sciences Institute
06-2017

High School Diploma -

Anadolu University Faculty of Pahrmacy
06-2015

Skills

Pharmacy ethics awareness

Academic research

Scientific writing

Analytical thinking

Awards

  • Akademik
  • Stün Başarı Ödülü, Anadolu
  • Niversitesi, 2021
  • Niversitesi, 2022
  • Bronz Madalya, 6th İstanbul International Inventions Fair (ISIF-21), 2021

Publications

  • Design, Synthesis, In Vitro and In Silico Studies of Some Novel Thiazole-Dihyrofuran Derivatives as Aromatase Inhibitors, Bioorganic Chemistry, 10.1016/j.bioorg.2021.105123, 2021
  • Design, synthesis, in vitro and in silico studies of some novel triazoles as anticancer agents for breast cancer, Journal of Molecular Structure, 10.1016/j.molstruc.2021.131198, 2021
  • Design, Synthesis and Biological Evaluation of New N‐Acyl Hydrazones with a Methyl Sulfonyl Moiety as Selective COX‐2 Inhibitors, Chemistry & Biodiversity, 10.1002/cbdv.202100521, 2021
  • Novel Thiosemicarbazone Derivatives: In Vitro and In Silico Evaluation as Potential MAO-B Inhibitors, Molecules, 10.3390/molecules26216640, 2021
  • Design, synthesis, in vitro, and in silico studies of 1, 2, 4-triazole-piperazine hybrid derivatives as potential MAO inhibitors, Bioorganic Chemistry, 10.1016/j.bioorg.2021.105430, 2021
  • Design, synthesis, and biological activity of novel dithiocarbamate‐methylsulfonyl hybrids as carbonic anhydrase inhibitors, Archiv der Pharmazie, 10.1002/ardp.202200132, 2022
  • Design and synthesis of novel chalcone derivatives and evaluation of their inhibitory activities against acetylcholinesterase, Archiv der Pharmazie, 10.1002/ardp.202100372, 2022
  • Design, synthesis, biological activity, molecular docking, and molecular dynamics of novel benzimidazole derivatives as potential AChE/MAO‐B dual inhibitors, Archiv der Pharmazie, 10.1002/ardp.202100450, 2022
  • Synthesis and biological evaluation of novel 1, 3, 4‐oxadiazole derivatives as anticancer agents and potential EGFR inhibitors, Journal of Heterocyclic Chemistry, 10.1002/jhet.4398, 2022
  • Synthesis of New Pyrimidine‐Triazole Derivatives and Investigation of Their Anticancer Activities, Chemistry & Biodiversity, 10.1002/cbdv.202200216, 2022

Application

Eczacılık Fakültesi, Eczacılık Meslek Bilimleri Bölümü, Farmasötik Kimya Anabilim Dalı, Sağlık Bilimleri Temel Alanı, 02/23/24, eKzZT9wAAAAJ, 0000-0002-0499-436X, ABC-7459-2022, 57193579046

Software

Molecular Docking and Molecular Dynamic Simulations

Timeline

Associate Professor of Pharmacy

Anadolu University
03.2017 - Current

Ph.D. - Medicinal And Pharmaceutical Chemistry

Anadolu University Health Sciences Institute

Master of Science - Medicinal And Pharmaceutical Chemistry

Anadolu University Health Sciences Institute

High School Diploma -

Anadolu University Faculty of Pahrmacy
Derya OsmaniyeAcademician