Arwa Ahmed Saleh Al.Adhreai

Accomplished Assistant Professor and researcher In Organic Chemistry with over 15 years of experience In academia and scientific research. She holds a Ph.D. In Organic Chemistry from Dr. Babasaheb Ambedkar Marathwada University (India), and ranked first in both her M.Sc. and B.Sc. studies at Thamar University (Yemen).

She has a strong background in teaching a wide range of undergraduate chemistry courses and mentoring students.

Recently completed a pancreatic cancer research project at a pharmaceutical company in Turkey, which led to the development of novel compounds and a patent currently under publication. In parallel with her academic career, she is actively engaged in drug discovery and pharmaceutical development, and has completed advanced professional training in Drug Development and Artificial Intelligence in Pharmaceutical Technology at Pfizer Pharmaceutical Company.
Her research interests include heterocyclic compound synthesis, 1,3-dipolar cycloaddition reactions, small-molecule therapeutics, and computational drug design. She is highly skilled in modern analytical and comp-utational tools including NMR, FTIR, UV-Vis, HPLC, LC-MS, molecular docking, and ADMET prediction. Dr. Arwa has authored and co-authored over 30 peer-reviewed scientific publications in high-impact journals and has presented her work in numerous international conferences. She has received several prestigious recognitions, including the President of the Republic's Award for Scientific Excellence.

• I received the President of the Republic's Award for being the best researcher in science at Dhamar University in the year 2012
• Postgraduate certificate in teaching way in higher education awarded by Dhamar University in 2011.

• Assistant Professor of Organic Chemistry, Faculty of Applied Science, Thamar University, Thamar, Yemen.

              https://www.tu.edu.ye/staff/#/home/dept- staff/343259c0-391e- 43fb-9f00-08ffaee9bb9

• Working on a pancreatic cancer project as a supervisor in a Turkish pharmaceutical manufacturing company ,Trustlife Labs ,Turkey

            https://www.trustlifeventures.com/en/rd-center

• Activated university teaching skills, Academic Development and Evaluation Division in Thamar University from 25 April - May 2010.
• Obtaining a training course at Pfizer Pharmaceutical Manufacturing Company titled "Artificial Intelligence in Pharmaceutical Technology and Drug Delivery Design from 10.10.2023-01.15.2024.

• Arwa AL Adhreai and other; Enhanced synthesis of novel multisubstituted isoxazolidines as potential antimicrobial and antioxidant agents using zinc (II) catalyst, and in silico studies. Journal of Molecular Structure (2023).
• Abdulwahab, A. M., Al-Adhreai, A. A. A., Al-Hammadi, A. H., Al-Adhreai, A., Salem, A., Alanazi, F. K., & ALSaeedy, M. (2025). Synthesis, characterization, and anti-cancer activity evaluation of Ba-doped CuS nanostructures synthesized by the co-precipitation method. RSC advances, 15(6), 4669-4680.
• Al-horaibi, Sultan A., Abdel-Basit Al-Odayni, Mohammed ALSaeedy, Fares Hezam Al-Ostoot, Adel Al-Salihy, Abdulmajeed Alezzy, Arwa Al-Adhreai, Faizaa A. Saif, Salama A. Yaseen, and Waseem Sharaf Saeed. "Exploring DSSC Efficiency Enhancement: SQI-F and SQI-Cl Dyes with Iodolyte Electrolytes and CDCA Optimization." Molecules 28, no. 20 (2023): 7129.
• Al-horaibi, Sultan A., Abdel-Basit Al-Odayni, Abdulmajeed Alezzy, Mohammed ALSaeedy, Arwa Al-Adhreai, Waseem Sharf Saeed, and Ahmed Hasan. "Novel Squaraine Dyes for High-Performance in Dye-Sensitized Solar Cells: Photophysical Properties and Adsorption Behavior on TiO2 with Different Anchoring Groups." Journal of Molecular Structure (2023): 135943.
• Arwa AL Adhreai and other; Novel hybrid Triazoline - Triazole Glycosides: Synthesis, Characterization, and Antimicrobial Activity Study via In Vitro and In Silico Means. Under published. Carbohydrate Research (2023).
• Al-Hammadi, A. H., Al-Adhreai, A. A. A., Abdulwahab, A. M., Al-Adhreai, A., Salem, A., Alaizeri, Z. M., ... & Katib Alanazi, F. (2024). An investigation on the structural, morphological, optical, and antibacterial activity of Sr: CuS nanostructures. Scientific Reports, 14(1), 25169.
• Al-Qadsy, Inas, Waseem Sharaf Saeed, Abdel-Basit Al-Odayni, Ali Alrabie, Lena Ahmed Saleh Al-Faqeeh, Arwa Al-Adhreai, Ahmad Abdulaziz Al-Owais, Abdelhabib Semlali, and Mazahar Farooqui. "Antidiabetic, antioxidant and cytotoxicity activities of ortho-and para-substituted Schiff bases derived from metformin hydrochloride: Validation by molecular docking and in silico ADME studies." Open Chemistry 21, no. 1 (2023): 20230125.
• Ali Alrabie, Nabeel Abdullah Alrabie, Mohammed AlSaeedy, Arwa Al-Adhreai, Mazahar Farooqui. Icp-Ms Analysis, Gc-Ms Identification Of Antimicrobial, Antioxidant, Antidiabetic Volatile Bioactive Constituents From Tribulus Terrestris Fruits. World Journal Of Pharmacy And Pharmaceutical Sciences (2023).
• Ali Alrabie*, Mohammed AlSaeedy, Arwa Al-Adhreai, Inas Al-Qadsy, Mazahar Farooqui. In Silico, Molecular Docking And In Vitro Antibacterial Activity Of Bioactive Compounds Of Aqueous Extract Of Caesalpinia Bonducella (L.) Roxb Seed Kernel. World Journal Of Pharmacy And Pharmaceutical Sciences.
• Arwa AL Adhreai , Mohammed ALsaeedy, Mazahar Farooquia, Ali Alrabie, Inas Al-Qadsy ,Usama Al- Timari. Stereoselectivity Synthesis and Characterization, ADMET, Molecular Docking Study and Antimicrobial Activity of Novel Chiral Open-Chain Sugar-Derived Nitrones and their 1,3-Dipolar Cycloaddition. Journal of Molecular Structure (2022).
• Arwa AL Adhreai and other; Design and Synthesis of Novel Enantiopure Bis(5- Isoxazolidine) Derivatives: Insights into Their Antioxidant and Antimicrobial Potential via In Silico Drug-Likeness, Pharmacokinetic, Medicinal Chemistry Properties, And Molecular Docking Studies , Heliyon. (2022)
• Al-Qadsy, I., Al-Odayni, A. B., Saeed, W. S., Alrabie, A., Al-Adhreai, A., Al- Faqeeh, L. A. S., ... & Farooqui, M. (2021). Synthesis, Characterization, Single- Crystal X-ray Structure and Biological Activities of [(Z)-N′-(4-Methoxybenzyl-idene) benzohydrazide–Nickel (II)] Complex. Crystals (2022).
• Arwa AL Adhreai and other (An Overview of Advances in the Chromatography of Drugs Impurity Profiling). Journal of Liquid Chromatography & Related Technologies (2022).
• Ali Alrabie, Nabeel Abdullah Alrabie, Mohammed AlSaeedy, Arwa Al-Adhreai, Inas Al-Qadsy, Sultan A. Al-Horaibi, ZabnAllah M. Alaizeri, Hisham A.Alhadlaq, Maqusood Ahamed & Mazahar Farooqui. An integrative GC-MS and LC-MS metabolomics platform determination of the metabolite profile of Bombax ceiba root, and in silico & in vitro evaluation of its antibacterial & antidiabetic activities. Natural Product Research (2022).
• Ali Alrabiea, Nabeel Abdullah Al-Rabie, Mohammed ALSaeedy, Arwa Al Adhreai, Inas Al-Qadsy, and Mazahar Farooqui. Martynia annua safety and efficacy: heavy metal profile, in silico and in vitro approaches on antibacterial and antidiabetic activities. Natural Product Research (2022).
• Arwa AL Adhreai and other; An overview of liquid chromatographic methods for analyzing new generation anti-epileptic drugs. Journal of Liquid Chromatography & Related Technologies (2022).
• Arwa AL Adhreai , Mohammed ALsaeedy, Mazahar Farooquia, Ali Alrabie, Inas Al-Qadsy ,Usama Al-Timari Regio-And Stereoselectivity of 1,3-Dipolar Cycloaddition Reaction of Cinnarizine Drug with Chiral Nitrones, and Their Antimicrobial Activity. Rasayan J. Chem (2021).
• Mohammed AlSaeedy, Arwa Al-Adhreai and others. Determination of Glycine and Glutamate in brain Microdialysis Samples by Liquid Chromatography with Coulometric Detection. Under published.
• Inas Al-Qadsy, Waseem Sharaf Saeed *, Abdel-Basit Al-Odayni, Ali Alrabie, Lena Ahmed Saleh Al-Faqeeh, Arwa Al-Adhreai. New pharmacological model antidiabetic and antioxidant based on metformin hydrochloride. Molecules.
• Inas Al-Qadsy, Waseem Sharaf Saeed *, Abdel-Basit Al-Odayni, Ali Alrabie, Lena Ahmed
• Saleh Al-Faqeeh, Mohammed ALSaeedy, Arwa Al-Adhreai. Synthesis and structure elucidation of Ni(II) and Zn(II) Schiff-base Complexes derived from (E)-2-((5-bromothiazol -2-yl) imino) methyl) phenol as potential antimicrobial candidates. Inorganics..
• Arwa AL Adhreai and other; A Critical Review for Analyses of the New Generation Anti-epileptic Drugs by Liquid Chromatographic Methods..
• Al-Madhagi, Haitham, Arwa Al-Adhreai, Mohammed ALSaeedy, Ali Alrabie, Sultan A. Al-horaibi, Zabn Allah M. Alaizeri, Hisham A. Alhadlaq, and Mazahar Farooqui. "Dual docking of some synthesized isoxazolidine derivatives against Cathepsin L and main protease as a novel treatment strategy for COVID-19." Journal of Molecular Structure 1300 (2024): 137253.
• Arwa Al Adhreai. Usama S.Altimari*, Synthesis and Identification of New Prepared Isoxazolidine by 1,3-Dipolar cycloaddition Reactions. AFAQ journal of Thamar University (2010) (5th Issue).
• Arwa Al Adhreai. Usama S. Altimari* Synthesis and Identification of Chiral open- chain Sugar-derived nitrones and their 1,3-dipolar cycloaddition with maleimide and maleic acid. college of health and Medical Technology journal, IRAQ (2012).
• Al-Hammadi, A. H., Asma’A. Ahmed Al-Adhreai, A. M. Abdulwahab, Arwa Al-Adhreai, Aeshah Salem, ZabnAllah M. Alaizeri, Mohammed ALSaeedy, and Faisal Katib Alanazi. "An investigation on the structural, morphological, optical, and antibacterial activity of Sr: CuS nanostructures." Scientific Reports 14, no. 1 (2024): 25169.
• Alezzy, Abdulmajeed A., Sultan A. Al-horaibi, Hanan A. Alnahari, Abdel-Basit Al-Odayni, Mohammed ALSaeedy, AL-Adhreai Arwa, Waseem Saeed, Gamal Alshawesh, and Pathan Mohd Arif. "Synthesis, characterization, and biological studies of novel N (cinnamylidene) sulfamethoxazole (SMZ-CAL) and its metal complexes." Journal of Molecular Structure 1299 (2024): 137069.
• Al-Qadsy, Inas, Waseem Sharaf Saeed, Ahmad Abdulaziz Al-Owais, Abdelhabib Semlali, Ali Alrabie, Lena Ahmed Saleh Al-Faqeeh, Mohammed ALSaeedy, Arwa Al-Adhreai, Abdel-Basit Al-Odayni, and Mazahar Farooqui. "Antimicrobial Activity of Novel Ni (II) and Zn (II) Complexes with (E)-2-((5-Bromothiazol-2-yl) imino) methyl) phenol Ligand: Synthesis, Characterization and Molecular Docking Studies." Antibiotics 12, no. 11 (2023): 1634
• Al-horaibi, Sultan A., Abdel-Basit Al-Odayni, Mohammed ALSaeedy, Fares Hezam Al-Ostoot, Adel Al-Salihy, Jawaher Q. Ghaleb, Arwa Al-Adhreai, Faizaa A. Saif, Salama A. Yaseen, and Waseem Sharf Saeed. "Enhancing photovoltaic efficiency with SQI-Br and SQI-I sensitizers: A comparative analysis." Open Chemistry 21, no. 1 (2023): 20230168..
• Alrabie, Ali, Mohammed ALSaeedy, Arwa Al-Adhreai, Inas Al-Qadsy, Abdel-Basit Al-Odayni, Waseem Sharaf Saeed, Ahmed Hasan, and Mazahar Farooqui. "Unraveling the therapeutic potential of Bombax ceiba roots: A comprehensive study of chemical composition, heavy metal content, antibacterial activity, and in silico analysis." Open Chemistry 21, no. 1 (2023): 20230179.

SYNTHESIS AND BIOLOGICAL ACTIVITY STUDY OF ISOXAZOLIDINE DERIVATIVES BY 1,3-DIPOLE CYCLOADDITION REACTIONS.

• Experience in organic chemistry (Design, Synthesis, Characterization and biological activities of Heterocyclic compounds).
• Synthesis and Identification Small Molecules
• Synthesis and structure of new organic compounds by used cycloaddition reactions.
• Heterocyclic chemistry; synthesis and applications.
• Synthesis and Identification of New Isoxazolidines by 1,3-Dipolar Cycloaddition reactions.
• Expertise in the characterization of organic compounds using NMR, IR, HPLC, and other analytical techniques

• National Lenel Conference And 16thAnnual Convenence of ACTRA”Multi-disciplinary Research Meet 2023 “ Chemistry Department, Kohinoor Arts, commerce&Science college Khultabad Dist, Aurangabade, India on 12th February 2023
• 15th Convention and National Level Seminar on Multi-disciplinary Approach in Research (MAR-2020), Chemistry Department, Dr. Rafiq Zakaria College for women Aurangabade, India, on 9thFeb.2020.
• International symposium on (Expolaring New Horizons in Chemical science (ENHCS-2019), Chemistry Department, Deogiri College Aurangabade, India, on 10th-12th Jan. 2019.
• 13th Annual Convention One day national seminar on “Recent Advancements in science” Chemistry Department, Saraswati Bhuvan Education Society college of science, Aurangabade, India, on 10th March 2019.
• Recent Advancements in science March 2019
• Recent developments in science January 2018
• Synthesis and Identification of New Prepared Isoxazolidine by 1,3-Dipolar cycloaddition Reactions, 1st Scientific International Conference-The University college of Humanities, Annajaf-Iraq.13-April 2016
• Synthesis and Identification and Biological Activity Study of New Prepared
• Isoxazolidine Derivatives, The sixth Jordanian international conference of chemistry Yarmouk University, Irbid-Jordan, 17-20 April 2011.
• Synthesis and Identification and Biological Activity Study of New Prepared Isoxazolidine Derivatives 6th International Conference of Chemistry, Chemistry Department, College of Science, Basrah-University- Basrah-Iraq, 2,3 November 2011.

• Writing a book entitled : Khat and chemical drug Issued in 2016 , with co-authorship Dr Mohamme ALsaeedy, Member at Dhamar University of Yemen

• Prof. Dr. Mazhar Farooqi

        Professor of Pharmaceutical Chemistry - President of the University Maulana Azad College of Arts Science -Aurangabad- India

        Email address : farooqafarooqa26@gmail.com

• Prof. Dr. Usama S.AL-Timari

        Professor of Organic Chemistry, Head of the Department of Pharmaceutical Chemistry, University of Babylon

          Email address: profusama84@gmail.com

• Prof. Dr. Daiekh A.AAbod Professor of Organic Chemistry , Head of the Department of Pharmaceutical Chemistry, Dhamar

      Email address : Daiekh A.AAbod@gmail.com